The corresponding laboratory results at 12 h postoperatively supported this conclusion (p < 0.05), with higher AST, ALT, sCr, cystatin C, and cTnI levels, a lower eGFR, and a longer prothrombin time (PT) in the severe-AKI cohort (p < 0.05). The gene discussed is TNNI3; the disease is acute kidney injury.