RBC: red blood cells; WBC: white blood cells; PLT: platelets; HGB: hemoglobin; anti-SSA antibodies: anti-Sjögren's syndrome A antibodies; anti-SSB antibodies: anti-Sjögren's syndrome B antibodies; antinuclear antibodies: autoantibodies targeting nuclear components; anticentromere antibodies: antibodies against centromere proteins; RF: rheumatoid factor; CRP: C-reactive protein. The gene discussed is TRIM21; the disease is Sjogren syndrome.