Our meta-analysis included 30 articles and thus constituted a wide-ranging evaluation of the relationships of ERCC1 C8092A, ERCC2 Lys751Gln, XRCC1 Arg399Gly, and XRCC3 T241M polymorphisms with the risk of glioma in various populations. The gene discussed is XRCC3; the disease is glioma.