Specifically, the mRNA expression level of hnRNPA1 was increased in the HCC cell (SMMC 7721 and Hep G2) compared with normal liver cells (L02 and LX-2), also the mRNA expression level of hnRNPA1 was increased in other cancer cells (U251, Hela and B16-F10) (p < 0.001) (Figure 1C). This evidence concerns the gene HNRNPA1 and cancer.