ESR1 and endometrial cancer: The results indicated that higher FIGO stage (HR = 5.088, 95% CI: 1.537–16.842), the presence of LVSI (HR = 2.430, 95% CI: 1.227–4.813), ER negativity (HR = 0.294, 95% CI: 0.121–0.717), and abnormal P53 expression (HR = 2.422, 95% CI: 1.279–4.587) were independent factors influencing early recurrence after surgery in patients with endometrial cancer, all with statistically significant results.