This effect was much more pronounced in isotype Ctrl- compared to anti-PD-L1-treated animals and possibly reflects an inflammatory response induced by the tumor or massive GCV-induced lysis of tumor cells (Balkwill and Mantovani, 2001; Mantovani et al., 2008; Vakkila and Lotze, 2004; Lupusoru et al., 2022). Here, CD274 is linked to neoplasm.