As mRNA expression of other markers for cardiac pathologic alterations, such as βMHC, and also Anp, Bnp and Col1a1 in the LV tissue of B16F10-GCV mice was not affected by PD-L1 inhibition, this rather suggests beneficial remodeling in the heart of mice, which are recovered from tumor disease, than a pathologic effect of PD-L1 inhibition. Here, NPPA is linked to neoplasm.