Cox univariate analysis of all clinical indicators revealed significant associations between OS and factors such as TCM usage, cirrhosis, HS, ascites, HE, PVTT, HBV-DNA, tumor number, tumor size, NLR, RBC, HGB, PSL, CR, AST, TBIL, ALB, LDH, GGT, ALP, CHE, PTA, AFP and CRP. The gene discussed is AFP; the disease is hereditary elliptocytosis.