The accumulation of ROS and intracellular labile iron can enhance the sensitivity of DLBCL tumor cells to ferroptosis (Huang et al., 2023), while ROS-induced oxidative stress can activate the NF-κB pathway, which is somewhat related to the pathogenesis of DLBCL (Lingappan, 2018; Compagno et al., 2009). Here, NFKB1 is linked to diffuse large B-cell lymphoma.