IL6 and non-small cell lung carcinoma: NSCLC CAFs 3 were classified as inflammatory CAFs based on the elevated expression of inflammatory factors, including complement factor D and cytokines interleukin-6 (IL-6), chemokine (C-C motif) ligand 2 (CCL2), and chemokine (C-X-C motif) ligand 2 (CXCL2).