CD226 and non-small cell lung carcinoma: In NSCLC, CAFs exert immunosuppressive effects on natural killer cells by reducing the surface levels of lysosomal-associated membrane protein-1/CD107, natural killer cell group 2D (NKG2D), natural cytotoxicity triggering receptor 1 (NKp46), and DNAX accessory molecule-1 (DNAM-1).101