NFKB1 and neoplasm: Studies indicate that Rg3 can activate various signaling pathways such as AMPK, JNK, NF‐κB, MAPKs, and the PI3K/AKT/mTOR axis, mediating pharmacological effects, including anti‐tumor activity, cardiovascular protection, immune regulation, neuroprotection, anti‐diabetic effects, anti‐fatigue, anti‐allergic responses, anti‐aging benefits, and antioxidant properties (Xu et al. 2023).