AKT1 and hypertrophic cardiomyopathy: In the OT versus EC comparison (Figure 13), a positive enrichment of pathways such as “Ras signaling pathway”, “PI3K-Akt signaling pathway”, “AMPK signaling pathway”, and “focal adhesion” were observed, while pathways like “axon guidance”, “hypertrophic cardiomyopathy”, “ECM-receptor interaction” and “tight junction” were negatively enriched.