PTK2 and neoplasm: The mechanisms by which FOXM1 promotes tumor growth in TNBC mainly include its regulation of the expression and activity of focal adhesion kinase (FAK) in TNBC cells (Hamurcu et al., 2017), and its direct binding to the promoter of the KIF23 gene to promote its transcription and accelerate TNBC progression via the Wnt/β-catenin pathway (Li Z. et al., 2022).