The Jariyasakulroj et al. study (2023) investigated the mechanistic role of the Snord118 in the context of a craniofacial birth defect known as craniosynostosis, which is a result of premature fusion of cranial sutures happening due to the loss of MSCs and an imbalance between bone formation and resorption at the cranial suture site (Jariyasakulroj et al., 2023). Here, SNORD118 is linked to craniosynostosis.