TP53 and neoplasm: Similar results were also obtained for NrasG12V;MycOE;Trp53–/– cells and cells derived from Akt1myr ;MycOE driven, Cdkn2aARF-deficient tumours (Akt1myr;MycOE;Cdkn2aARF–/–) (Extended Data Fig. 2c,d).