Furthermore, our results revealed that GPX8-high patients with high CD4+ T cell infiltration in COAD exhibited a shorter survival time compared to those with low CD4+ T cell infiltration (P = .0392), which was similar to GPX8-high patients in STAD with high neutrophil infiltration compared to those with low neutrophil infiltration (P = .036) (Fig. 3C). The gene discussed is GPX8; the disease is gastric adenocarcinoma.