The immunohistochemical results for tumor and normal tissues from representative patients are displayed in Figure 4A. As shown in Figure 4B, GPX8 expression was significantly higher in tumor tissues compared to adjacent normal tissues in both STAD (t = ‐12.024, P < .001) and COAD (t = ‐3.340, P = .002). This evidence concerns the gene GPX8 and neoplasm.