PRAL and obesity due to melanocortin 4 receptor deficiency: While research on the correlation between PRAL and TyG-BMI is limited, a meta-analysis indicated that a high DAL is linked to increased serum triglyceride levels and a higher prevalence of obesity.[19] Also, the research conducted by Rezazadegan et al in 2022 indicated that DAL, measured by PRAL and NEAP, could be linked to an increased likelihood of developing an unhealthy phenotype in overweight or obese adolescents.