CXCL8 and hepatocellular carcinoma: Peng et al. reported that lncRNA PANDA overexpression promoted proliferation and carcinogenic effects in HCC both in vitro and in vivo. Mechanistically, PANDA inhibited the transcriptional activity of the senescence-associated inflammatory factor IL-8, thereby suppressing senescence in HCC cells (Peng et al., 2017).