In another study, N‐butyl‐N‐(4‐hydroxybutyl) nitrosamine was used to induce bladder cancer and it was noted that luteolin is markedly lowered the tumor dimension, inhibited cell proliferation and mTOR signaling, lowered the Ki67‐labeling index and p‐S6 expressions (Iida et al. 2020). This evidence concerns the gene MKI67 and neoplasm.