2007). Rao et al. (2012) observed that luteolin suppresses the cell proliferation and induces apoptosis in different cancer cells through Akt, c‐Jun N‐terminal kinases, and p38. A potent tumor suppressor, miR‐106a‐5p, is newly discovered miRNA to have a role in suppression of epithelial‐mesenchymal transition is upregulated by luteolin and negatively regulated MMP2 and TWIST1 migration and have a critical role in anticancer strategies (Wang et al. 2024). This evidence concerns the gene MMP2 and neoplasm.