It was summarized that some lncRNAs have oncogenic effects, such as MALAT1 and XIST (106, 107), which trigger the development of colorectal cancer; and the other part of lncRNAs have oncogenic effects, such as GAS5 and MEG3 (63, 85), inhibitory effects on cell proliferation and invasion in CRC. Here, MEG3 is linked to colorectal cancer.