Among the screened literature, five lncRNAs including XIST, SLC7A11-AS1, NEAT1, MALAT1 and CCAT2, PVT1, and SNHG11 have been reported to be up-regulated in CRC in several papers, MALAT1 (48, 64–66) and NEAT1 (39, 67–69) were reported to be overexpressed in four papers, respectively.MALAT1 showed higher levels in tumor tissues and was associated with metastasis in CRC patients (48) PVT1, SNHG11 is significantly upregulated in CRC patients (64, 70) PVT1, SNHG11. The gene discussed is XIST; the disease is neoplasm.