It was summarized that some lncRNAs have oncogenic effects, such as MALAT1 and XIST (106, 107), which trigger the development of colorectal cancer; and the other part of lncRNAs have oncogenic effects, such as GAS5 and MEG3 (63, 85), inhibitory effects on cell proliferation and invasion in CRC. The gene discussed is MALAT1; the disease is colorectal carcinoma.