CYP3A4 and B-cell chronic lymphocytic leukemia: Figure 1 present suggested algorithm for assessment CLL treatment in case of use of CYP3A4 inhibitors/inducers (Tam et al., 2022b; Al-Sawaf et al., 2024; Ramanathan et al., 2016; Awan et al., 2020b; Brown et al., 2022).