It was found that CDK1 overexpression in adrenocortical carcinoma cell (ACC) lines locked ACC cells at the G2/M checkpoint by interacting with UBE2C and AURKA/B, promoting cancer cell proliferation and inducing epithelial mesenchymal transition (EMT) (Ren et al., 2022). The gene discussed is CDK1; the disease is adrenal cortex carcinoma.