CBS and neoplasm: Significant differences in the proliferation rates were observed between TP53‐WT and the C176F mutant, TAAO‐WT and T42S, GUSB‐WT and H351Q, and CBS‐WT and D238E, among which GUSB‐H351Q dramatically promoted tumor cell growth compared with that of the cells expressing GUSB‐WT and the vector (Figure 2A–I).