While αSMA-positive myofibroblasts are observed in the early stages following myocardial infarction, they are absent at later time points in other models such as transverse aortic constriction (TAC), e.g., at day 14 or 28,15 and angiotensin II (AngII) infusion at day 14.16 The gene discussed is AGT; the disease is myocardial infarction.