Similarly, there was a progressive increase in PTHrP H score values from normal breast (mean ± SD 97.97 ± 37.18, median of 80.0) to adjacent DCIS lesions (mean ± SD 186.5 ± 36.77, median of 195.0) peaking in IBC-NST cases (mean ± SD 209.51 ± 49.86, median of 210.0) (p < 0.001). The gene discussed is PTHLH; the disease is ductal breast carcinoma in situ.