CUL1 and neoplasm: We found that rs76011559 mapping to 7q36.1 (123 kb upstream of CUL1) replicated in patients with proximal tumours (Hazard Ratio [HR] = 1.31, 95% Confidence Intervals [CI] = 1.03–1.66, P = 2.8 × 10–2, Supplementary Fig. 1, Table 2).