As shown in Fig. 4I-M and Fig. S4F-H, DUB3 depletion in A2780 and SKOV3 cells significantly decreased cell proliferation and sensitized cancer cells to cisplatin in vitro and in vivo, whereas reconstitution of YAP1 in DUB3-depleted cells could markedly rescued these phenotypical changes. Here, YAP1 is linked to cancer.