Notably, among the seven CpG sites liked to the diabetes progression, five showed a negative correlation with gene expression levels, including cg23436042, cg11183227 (MAN2A2), cg06500161 (ABCG1), cg06710464 (BAIAP2), and cg17058475 (CPT1A), while cg08788930 (DENND3) and cg11311053 (NCOR2) did not. The gene discussed is ABCG1; the disease is diabetes mellitus.