CD8A and neoplasm: Concomitantly, a significant decrease is observed in the infiltration of myeloid-derived suppressor cells (MDSCs), RORγ+Th17 cells, and CD11b+CD11c+ suppressive myeloid cells within the TME following FMT intervention.7,77–80 Studies have indicated that following FMT, patients exhibit elevated levels of CD4+ and CD8+ T cells, while Tregs levels diminish.81 The ratio of intratumoral CD8+ T cell to Treg infiltration is elevated in patients following FMT.82 This modification in immune cell composition promotes the formation of an anti-tumor immune microenvironment.