IL17A and hepatocellular carcinoma: Another L. reuteri produced metabolite, the SCFA acetate, was able to reduce tumor burden in a murine hepatocellular carcinoma (HCC) model by inhibiting IL-17A production.73L. reuteri administration decreased overall IL-17A levels in serum and selectively reduced the IL-17A production of hepatic ILC3s, but not thymic or splenic cells.