The investigated genes including SLC11A1 (523-bp), TLR1 (471-bp), TLR9 (460-bp), SP110 (537-bp), ADORA3 (521-bp), CARD15 (394-bp), IRF3 (468-bp), GPX1 (420-bp), NOS (332-bp), NQO1 (466-bp), Nrf2 (480-bp), TKT (414-bp), RPIA (338-bp), and AMPD (382-bp) genes showed nucleotide sequence variations, which are polymorphic SNPs that may be associated with brucellosis susceptibility in the does under investigation. Here, RPIA is linked to brucellosis.