However, multiple logistic regression showed that only meningitis (adjusted OR 11.53, p = 0.01),need for fluid bolus (adjusted OR 16.8, P 0.01), and peak CRP (adjusted OR 1.01, p = 0.03) were significant predictors of combined death and neurodisability, when adjusted for birth weight, gestational age, gender, leukopenia, thrombocytopenia and need for positive pressure ventilation at birth (Table 7). This evidence concerns the gene CRP and meningitis.