The elevated levels of lipid peroxidation in CD4+ T cells in the LR group may be due to the fact that HIV is more prone to infecting cells with high levels of mitochondrial oxidation [35], and also that HIV infection and replication further alters the levels of mitochondrial lipid peroxidation, impairs immune recovery in HIV patients, and increases the risk of sustained replication of residual viruses. This evidence concerns the gene CD4 and HIV infectious disease.