Five and nine PVs of BRCA1 and BRCA2, respectively, were not identified in our previous dataset from 3 352 participants (3.5KJPNv2) (ref. [28]), in a report using samples from the Biobank Japan (7 051 breast cancer patients and 11 241 controls) (ref. [25]), in the HBOC registration system of Japan reported in 2018 (127 and 115 BRCA1 and BRCA2 PV carriers, respectively) (ref. [26]), and in Japanese ovarian cancer patients (ref. [27]). Here, BRCA2 is linked to breast carcinoma.