Furthermore, compared with those in saline-treated tumor-bearing mice, highly significant decreases in the serum alkaline phosphatase (ALP), alanine transaminase (ALT) and aspartate transaminase (AST) levels and simultaneous elevation in the serum albumin concentration were observed after mice treatment with the mushroom PS compared with those of the saline-treated tumor-bearing mice. This evidence concerns the gene ALB and neoplasm.