Similarly, elevating the expression levels of BRSK2(Serine/threonine-protein kinase BRSK2) (OR = 1.30; P = 1.70 × 10−13) also increased the risk of ILD, while increasing the expression levels of ADAM15(A disintegrin and metalloproteinase 15) (OR = 0.86, 95% CI 0.81–0.92; P = 1.59 × 10−6) and LRRC37A2(Leucine-rich repeat-containing protein37A2) (OR = 0.82; P = 7.40 × 10−8) decreased the risk of ILD. Here, ADAM15 is linked to interstitial lung disease.