BRSK2 and sarcoidosis: In addition to BRSK2, sarcoidosis also demonstrated a reverse causal association with ANGPTL4 (βIVW = -0.03, p = 0.016), and the absence of heterogeneity (pQ = 0.12, ppleiotropy = 0.86) further reduced the likelihood of false-positive results and suggested that this reverse causal effect was not contributed by individual SNP.