To further confirm the importance of FABP4 and UCP2, differential gene expression analysis (Fig. 3A) was conducted using the GEO dataset GSE82236, which comprises RNA-seq data from both cetuximab-sensitive (CC; n = 3) and cetuximab-resistant colon cancer (CC—CR; n = 3) samples. This evidence concerns the gene FABP4 and malignant colon neoplasm.