FMR1 and fragile X syndrome: The temporal coordination of neuronal activity is manifested in the rhythmic oscillations of the local field potential (LFP).[43] Neural oscillations have been linked to cognitive and mechanistic processes throughout the brain, encompassing neuronal communication and precise spike timing of neuronal groups.[44, 45, 46] Abnormal spike‐phase locking and phase‐amplitude coupling (PAC) have been detected in FXS mice,[47] which is associated with impaired E‐I balance.[8, 48] As a result, we examined the temporal coordination of hippocampal oscillatory rhythms in WT, Fmr1‐KO, and Fmr1‐KO+MGE mice.