AKT1 and cancer: As FMRP regulates the synthesis of Ras‐PI3K/PKB signaling molecules, its absence inevitably leads to defects in synaptic Ras transport and/or function.[39, 67] Dysregulated Ras‐PI3K/PKB signaling is implicated in several characteristics of FXS, including spinal abnormalities, facial deformities, and the paradoxical reduction in cancer incidence observed in these patients.[68, 69, 70]