We observed that infection mediated by WT HIV-1 was potently inhibited by Nup62 blockade, but infection mediated by N74D and P90A CA mutant viruses was comparatively less sensitive or insensitive to the Nup62-mediated NPC blockade, suggesting the utilization of distinct nuclear import pathways, likely utilizing different NPCs [40]. This evidence concerns the gene NUP62 and infection.