The results showed no significant correlation between the BEISA signal and either CEA or CA19‐9 levels (rCEA = 0.330, PCEA = 0.075; rCA19‐9 = 0.157, PCA19‐9 = 0.408), highlighting that the platform provided a diagnostic strategy independent of traditional tumor markers and enhanced the accuracy and specificity of GC detection. The gene discussed is CEACAM5; the disease is neoplasm.