In the training set, the BEISA signal showed no significant correlation with either CEA and CA19‐9 (rCEA = 0.246, PCEA = 0.103; rCA19‐9 = 0.087, PCA19‐9 = 0.572), demonstrating that the platform provides a diagnostic method independent of traditional tumor markers and is able to enhance the accuracy and specificity of GC detection. This evidence concerns the gene CEACAM5 and neoplasm.