MYC and head and neck squamous cell carcinoma: Notably, we found that squamocin exhibited diverse effects on cells with different levels of MYC expression in that it had a high inhibitory on HNSCC cell lines with high levels of MYC (CAL27, FADU, SCC15, and SCC25), and a weak effect on noncancerous cell lines with low MYC expression (NOK and HUVEC) (Figure S2A, Supporting Information).