In the univariate analysis, male gender (HR = 1.211, P = 0.028), cirrhosis status (HR = 1.433, P = 0.014), ECOG performance status (HR = 1.925, P = 0.003), diabetes status (HR = 3.220, P < 0.001), higher levels of ALT (HR = 1.012, P = 0.024), larger tumor size (HR = 1.538, P < 0.001), multiple tumors (HR = 2.034, P < 0.001), and later tumor stage (HR = 1.271, P = 0.024) were associated with worse OS. The gene discussed is GPT; the disease is neoplasm.