In 2015, Salaria andcollaborators showed that both small intestine tumors and PanNENs express CD24, astem cell marker present in normal and tumoral (e.g., PDAC) stem cells (Salaria et al. 2015).Islets did not express this marker, and while 5% of included PanNENs exhibitedstrong subnuclear CD24 staining, the majority of the tumor cells stained positive,thus reducing the possibility that these CD24-positive cells represented a scarcepopulation of PanNEN CSCs. This evidence concerns the gene CD24 and small intestine neoplasm.