Like Czaja's and Domerecka's observations, the International Autoimmune Hepatitis Group (IAHG) has a diagnostic criterion that requires serum aspartate (AST) and alanine aminotransferase (ALT) abnormalities with elevated serum IgG levels and positive autoimmune serological investigations such as ANA, smooth muscle antibodies (SMA), and anti-LKM1 [5,6]. The gene discussed is SMN1; the disease is autoimmune hepatitis.