GFAP and astrocytoma (excluding glioblastoma): However, the molecular mechanism underlying the elevated expression of GFAP in astrocytes remains unclear, and studies employing in vitro models to explore GFAP's impact on cell proliferation yield inconclusive results [54], previous evidence has suggested that GFAP expression profoundly influenced cell morphology and suppressed cell growth in C6 cells, implying a potential tumor-suppressing role for GFAP in astrocytoma [55].