BDH1 and Sepsis: The myocardial concentrations of ketone body 3-hydroxybutyrate (Fig. 4.1) and acetoacetate (Fig. 4.3) were unaltered in prolonged sepsis, but gene expression of the converting enzyme 3-hydroxybutyrate dehydrogenase (Bdh1; Fig. 4.2) was increased in acute and prolonged sepsis.