Although soluble adhesion molecules like ICAM-1 and VCAM-1 are associated with sepsis severity, their sensitivity and specificity for sepsis-induced endothelial damage and organ dysfunction are not high in DIC, and their performance may not be superior to other sepsis biomarkers like procalcitonin or interleukin-6 [57]. The gene discussed is VCAM1; the disease is Sepsis.