DSG3 and pemphigus vulgaris: There are two main subtypes of pemphigus vulgaris: (1) mucosal PV, characterized by mucosal lesions caused by anti-Dsg3 autoantibodies, and (2) mucocutaneous PV, characterized by both mucosal and skin lesions caused by both anti-Dsg3 and anti-Dsg1 autoantibodies [55].