REN and Hypertension: Hypertension in neonates is normally seen in 0.2–3% of all infants, and because of the low prevalence in otherwise healthy term infants routine blood pressure (BP) determination is not recommended in this age bracket.4 Common causes of hypertension in neonates include thromboembolic events and congenital problems such as structural renal malformations, renovascular disease, and CoA.5 Hypertension in patients with CoA is likely to be multifactorial and related to a combination of innate abnormalities of the aortic wall and regulatory alterations of renin-angiotensin and baroreceptor systems.3