The tumor entity was confirmed by H&E and by immunohistochemical staining for HepPar1, as a marker for hepatocellular carcinoma, cytokeratin 7 (CK7), used as a marker for cholangiocarcinoma, and Picro-Sirius Red, as collagen stain (Supplementary Fig. 1). This evidence concerns the gene KRT7 and hepatocellular carcinoma.