To this end, our data demonstrated that DXM induces fatty liver and this effect is most likely associated with altered expression of FASN and CD36. To validate our in silico results, we investigated the effect of DXM and/or LG on FASN and CD36 at the DNA level using real-time quantitative reverse transcription PCR (RT-qPCR). Here, CD36 is linked to Hepatic steatosis.